Low-intensity electromagnetic fields induce human cryptochrome to modulate intracellular reactive oxygen species.

ABSTRACT: Exposure to man-made electromagnetic fields (EMFs), which increasingly pollute our environment, have consequences for human health about which there is continuing ignorance and debate. Whereas there is considerable ongoing concern about their harmful effects, magnetic fields are at the same time being applied as therapeutic tools in regenerative medicine, oncology, orthopedics, and neurology. This paradox cannot be resolved until the cellular mechanisms underlying such effects are identified. Here, we show by biochemical and imaging experiments that exposure of mammalian cells to weak pulsed electromagnetic fields (PEMFs) stimulates rapid accumulation of reactive oxygen species (ROS), a potentially toxic metabolite with multiple roles in stress response and cellular ageing. Following expos

SUBMITTER: Sherrard RM 

PROVIDER: S-EPMC6168118 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature