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A nested compartmental model to assess the efficacy of paratuberculosis control measures on U.S. dairy farms.


ABSTRACT: Paratuberculosis, also known as Johne's disease (JD), is a chronic contagious disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP). The disease is incurable, fatal and causes economic losses estimated to exceed 200 million dollars to the U.S. dairy industry annually. Several preventive and control measures have been recommended; however, only a few of these measures have been validated empirically. Using a nested compartmental (NC) modeling approach, the main objective of this research was to identify the best combination of control and preventive measures that minimizes the prevalence and incidence of JD and the risk of MAP occurrence in a dairy herd. The NC model employs both MAP transmission estimates and data on pen movement of cattle on a dairy to quantify the effectiv

SUBMITTER: Konboon M 

PROVIDER: S-EPMC6168138 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature