Spider silk proteome provides insight into the structural characterization of Nephila clavipes flagelliform spidroin.

ABSTRACT: The capture spiral of web from N. clavipes spider consists of a single type of spidroin - the flagelliform silk protein, a natural material representing a combination of strength and high elasticity. Flagelliform spider silk is the most extensible silk fibre produced by orb weaver spiders and the structure of this remarkable material is still largely unknown. In the present study we used a proteomic approach to elucidate the complete sequence and the post-translational modifications of flagelliform silk proteins. The long sequence of flagelliform silk protein presents 45 hydroxylated proline residues, which may contribute to explain the mechanoelastic property of these fibres, since they are located in the GPGGX motif. The 3D-structure of the protein was modelled considering the three doma

SUBMITTER: Dos Santos-Pinto JRA 

PROVIDER: S-EPMC6168590 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature