Physical activity, sedentary behaviour and risk of oesophago-gastric cancer: A prospective cohort study within UK Biobank.

ABSTRACT:

Background

Few observational studies have assessed the role of physical activity in oesophago-gastric cancer risk.

Objective

This prospective cohort study aimed to assess the association between physical activity and risk of oesophageal or gastric cancer.

Methods

A cohort of 359,033 adults aged 40-69 years were identified from the UK Biobank, which recruited participants between 2006 and 2010. Adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for the associations between self-reported levels of physical activity and screen-based sedentary behaviour and risk of oesophageal and gastric cancer were calculated using Cox proportional hazards models.

Results

During eight years of follow-up (mean = 5.5), 294 oesophageal cancer and 217 gastric cancer case

SUBMITTER: Kunzmann AT 

PROVIDER: S-EPMC6169059 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature