Adjacent segment degeneration or disease after cervical total disc replacement: a meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Anterior cervical discectomy and fusion (ACDF) has been widely used in cervical spondylosis, but adjacent segment degeneration/disease (ASD) was inevitable. Cervical total disc replacement (TDR) could reduce the stress of adjacent segments and retard ASD in theory, but the superiority has not been determined yet. This analysis aimed that whether TDR was superior to ACDF for decreasing adjacent segment degeneration (ASDeg) and adjacent segment disease (ASDis).

Methods

A meta-analysis was performed according to the guidelines of the Cochrane Collaboration with PubMed, EMBASE, Cochrane Library and CBM (China Biological Medicine) databases. It included randomized controlled trials (RCTs) that reported ASDeg, ASDis, and reoperation on adjacent segments after TDR and AC

SUBMITTER: Xu S 

PROVIDER: S-EPMC6169069 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature