Prognostic value of the fibrinogen/albumin ratio (FAR) in patients with operable soft tissue sarcoma.

ABSTRACT:

Background

Coagulation and nutrition play important roles in cancer progression. The aim of the present study is to evaluate the prognostic value of the preoperative fibrinogen/albumin ratio (FAR) in surgical patients with soft tissue sarcoma (STS) and to compare this value with other inflammatory biomarkers. In addition, we investigated the relationship between FAR and the clinicopathological characteristics of STS patients.

Methods

We included 310 STS patients in this retrospective study. Kaplan-Meier curves, univariate and multivariate Cox proportional models were used in the prognostic analyses.

Results

According to the receiver operating characteristic (ROC) analysis, the optimal FAR cut-off value was 0.0726. The FAR exhibited a greater area under the curve (AUC)

SUBMITTER: Liang Y 

PROVIDER: S-EPMC6169079 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature