Obesity Is Associated with Early Onset of Gastrointestinal Cancers in California.

ABSTRACT:

Background

Although it is well known that obesity is a risk factor for gastrointestinal (GI) cancer, it is not well established if obesity can cause earlier GI cancer onset.

Methods

A cross-sectional study examining the linked 2004-2008 California Cancer Registry Patient Discharge Database was performed to evaluate the association between obesity and onset age among four gastrointestinal cancers, including esophageal, gastric, pancreatic, and colorectal cancers. Regression models were constructed to adjust for other carcinogenic factors.

Results

The diagnosis of obesity (BMI > 30) was associated with a reduction in diagnosis age across all four cancer types: 3.25 ± 0.53 years for gastric cancer, 4.56 ± 0.18 years for colorectal cancer, 4.73 ± 0.73 years for esophageal

SUBMITTER: Juo YY 

PROVIDER: S-EPMC6169206 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature