Highly Contiguous Genome Assemblies of 15 Drosophila Species Generated Using Nanopore Sequencing.

ABSTRACT: The Drosophila genus is a unique group containing a wide range of species that occupy diverse ecosystems. In addition to the most widely studied species, Drosophila melanogaster, many other members in this genus also possess a well-developed set of genetic tools. Indeed, high-quality genomes exist for several species within the genus, facilitating studies of the function and evolution of cis-regulatory regions and proteins by allowing comparisons across at least 50 million years of evolution. Yet, the available genomes still fail to capture much of the substantial genetic diversity within the Drosophila genus. We have therefore tested protocols to rapidly and inexpensively sequence and assemble the genome from any Drosophila species using single-molecule sequenc

SUBMITTER: Miller DE 

PROVIDER: S-EPMC6169393 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature