Impact of bariatric surgery on neural food processing and cognition: an fMRI study.

ABSTRACT:

Introduction

The Roux-en-Y gastric bypass (RYGB) is one of the most widely used techniques for bariatric surgery. After RYGB, weight loss up to 50%-70% of excess body weight, improvement of insulin-resistance, changes in food preferences and improvements in cognitive performance have been reported. This protocol describes a longitudinal study of the neural correlates associated with food-processing and cognitive performance in patients with morbid obesity before and after RYGB relative to lean controls.

Methods and analysis

This study is a pre-post case-control experiment. Using functional MRI, the neural responses to food stimuli and a working memory task will be compared between 25 patients with obesity, pre and post RYGB, and a matched, lean control group. Resting state f

SUBMITTER: Schulze M 

PROVIDER: S-EPMC6169753 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature