Impact of pre-eclampsia on the cardiovascular health of the offspring: a cohort study protocol.

ABSTRACT:

Introduction

Pre-eclampsia is a common disorder associated with serious maternal and fetal complications. It is associated with abnormal placentation, which significantly reduces flow, resulting in a relative hypoxic state. These pathophysiological changes lead to subtle macrovascular and cardiac structural and functional changes in the fetus. This can predispose the child with maternal history of pre-eclampsia to risk of premature cardiovascular disease.

Methods and analysis

The children will be identified from a cohort of women with pre-eclampsia. The study will be conducted at The Aga Khan University Hospital, Karachi. Inclusion criteria will be children who are between 2 and 5 years of age and have a maternal history of pre-eclampsia. The child's current weight, height a

SUBMITTER: Hoodbhoy Z 

PROVIDER: S-EPMC6169754 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature