Association of oral ciprofloxacin, levofloxacin, ofloxacin and moxifloxacin with the risk of serious ventricular arrhythmia: a nationwide cohort study in Korea.

ABSTRACT:

Objective

To evaluate whether oral ciprofloxacin, levofloxacin, ofloxacin and moxifloxacin increase the risk of ventricular arrhythmia in Korea's general population.

Design

Population-based cohort study using administrative claims data on a national scale in Korea.

Setting

All primary, secondary and tertiary care settings from 1 January 2015 to 31 December 2015.

Participants

Patients who were prescribed the relevant study medications at outpatient visits.

Primary outcome measures

Each patient group that was prescribed ciprofloxacin, levofloxacin, ofloxacin or moxifloxacin was compared with the group that was prescribed cefixime to assess the risk of serious ventricular arrhythmia (ventricular tachycardia, fibrillation, flutter and cardiac arrest). Using

SUBMITTER: Cho Y 

PROVIDER: S-EPMC6169761 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature