Associations of clothing size, adiposity and weight change with risk of postmenopausal breast cancer in the UK Women's Cohort Study (UKWCS).

ABSTRACT:

Objectives

Breast cancer is associated with overweight and obesity after menopause. However, clothing size as a proxy of adiposity in predicting postmenopausal breast cancer is not widely studied. We aimed to explore the relationships between postmenopausal breast cancer risk with adipose indicators (including clothing sizes) and weight change over adulthood.

Design

Prospective cohort study.

Setting

England, Wales and Scotland.

Participants

17 781 postmenopausal women from the UK Women's Cohort Study.

Primary outcome measure

Incident cases of malignant breast cancers (International Classification of Diseases (ICD) 9 code 174 and ICD 10 code C50).

Results

From 282 277 person-years follow-up, there were 946 incident breast cancer cases with an incid

SUBMITTER: Moy FM 

PROVIDER: S-EPMC6169772 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature