Systemic inflammation and eye diseases. The Beijing Eye Study.

ABSTRACT:

Purpose

Systemic inflammation is potentially associated with ocular diseases such as late age-related macular degeneration (AMD). Using the serum concentration of high-sensitive C-reactive protein (hs-CRP) as surrogate of systemic inflammation, we examined potential associations between the serum hs-CRP concentration and the presence and degree of eye diseases.

Methods

The population-based Beijing Eye Study included 3468 Chinese individuals. The study participants underwent a standardized interview and a detailed ophthalmic examination. The serum concentration of hs-CRP was determined.

Results

Out of 3468 participants, 2452 (70.7%) individuals (mean age:63.4±9.4 year; range:50-91 years) had hs-CRP measurements (mean:1.96±4.07mg/L). In multivariate analysis, higher ser

SUBMITTER: Jonas JB 

PROVIDER: S-EPMC6169913 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature