Structural characterization of four different naturally occurring porcine collagen membranes suitable for medical applications.

ABSTRACT: Collagen is the main structural element of connective tissues, and its favorable properties make it an ideal biomaterial for regenerative medicine. In dental medicine, collagen barrier membranes fabricated from naturally occurring tissues are used for guided bone regeneration. Since the morphological characteristics of collagen membranes play a crucial role in their mechanical properties and affect the cellular behavior at the defect site, in-depth knowledge of the structure is key. As a base for the development of novel collagen membranes, an extensive morphological analysis of four porcine membranes, including centrum tendineum, pericardium, plica venae cavae and small intestinal submucosa, was performed. Native membranes were analyzed in terms of their thickness. Second harmonic generat

SUBMITTER: Maurer T 

PROVIDER: S-EPMC6169977 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature