Portable bacteria-capturing chip for direct surface-enhanced Raman scattering identification of urinary tract infection pathogens.

ABSTRACT: Acute urinary tract infections (UTIs) are one of the most common nosocomial bacterial infections, which affect almost 50% of the population at least once in their lifetime. UTIs may lead to lethal consequences if they are left undiagnosed and not properly treated. Early, rapid and accurate uropathogens detection methods play a pivotal role in clinical process. In this work, a portable bacteria-grasping surface-enhanced Raman scattering (SERS) chip for identification of three species of uropathogens (Escherichia coli CFT 073, Pseudomonas aeruginosa PAO1 and Proteus mirabilis PRM1) directly from culture matrix was reported. The chip was firstly modified with a positively charged NH₃ ⁺ group, which enables itself grasp the negatively charged bacteria

SUBMITTER: Yang D 

PROVIDER: S-EPMC6170559 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature