Physical function improvements with moderate or high-intensity exercise among older adults with or without HIV infection.

ABSTRACT:

Objective

Whether older people living with HIV (PLWH) can achieve similar functional benefits with exercise as their uninfected peers and the ideal intensity of exercise needed for these benefits are not known.

Design

Sedentary adults (50-75 years) with or without HIV were recruited for 24 weeks of supervised endurance/resistance exercise. After 12 weeks of moderate-intensity exercise, participants were randomized to continue moderate-intensity or advance to high-intensity exercise for an additional 12 weeks.

Methods

Outcomes by serostatus and exercise intensity (moderate, high) were compared using linear and mixed effects regression models and controlled for baseline values or week 12 values.

Results

A total of 32 PLWH and 37 controls were enrolled; 27 PLWH (1

SUBMITTER: Erlandson KM 

PROVIDER: S-EPMC6170687 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature