Presenting Characteristics Associated With Outcome in Children With Severe Traumatic Brain Injury: A Secondary Analysis From a Randomized, Controlled Trial of Therapeutic Hypothermia.

ABSTRACT:

Objectives

To identify injury patterns and characteristics associated with severe traumatic brain injury course and outcome, within a well-characterized cohort, which may help guide new research and treatment initiatives.

Design

A secondary analysis of a phase 3, randomized, controlled trial that compared therapeutic hypothermia versus normothermia following severe traumatic brain injury in children.

Setting

Fifteen sites in the United States, Australia, and New Zealand.

Patients

Children (< 18 yr old) with severe traumatic brain injury.

Measurements and main results

Baseline, clinical, and CT characteristics of patients (n = 77) were examined for association with mortality and outcome, as measured by the Glasgow Outcome Scale-Extended Pediatric Revision

SUBMITTER: Rosario BL 

PROVIDER: S-EPMC6170689 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature