MITE Tracker: an accurate approach to identify miniature inverted-repeat transposable elements in large genomes.

ABSTRACT:

Background

Miniature inverted-repeat transposable elements (MITEs) are short, non-autonomous class II transposable elements present in a high number of conserved copies in eukaryote genomes. An accurate identification of these elements can help to shed light on the mechanisms controlling genome evolution and gene regulation. The structure and distribution of these elements are well-defined and therefore computational approaches can be used to identify MITEs sequences.

Results

Here we describe MITE Tracker, a novel, open source software program that finds and classifies MITEs using an efficient alignment strategy to retrieve nearby inverted-repeat sequences from large genomes. This program groups them into high sequence homology families using a fast clustering algorithm and

SUBMITTER: Crescente JM 

PROVIDER: S-EPMC6171319 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature