The validity of self-reported antiretroviral use in persons living with HIV: a population-based study.

ABSTRACT:

Objective

To assess the validity of self-reported antiretroviral therapy use (ART) using population-based cohort data.

Methods

Self-reported ART use and nonuse was compared with a validated laboratory assay in 557 HIV-positive participants in the Rakai Community Cohort Study surveyed between September and December 2011 in Rakai, Uganda. The study population included participants from seven communities, including one fishing community with high HIV prevalence (∼41%). ART use was assayed using liquid chromatography-tandem mass spectrometry, which detects 20 antiretroviral drugs. HIV viral load measurements were also obtained. Individuals with at least two antiretroviral drugs detected were considered to be using ART.

Results

One hundred and fifty-three (27%) participant

SUBMITTER: Grabowski MK 

PROVIDER: S-EPMC6171354 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature