Nanoscale Functionalized Particles with Rotation-Controlled Capture in Shear Flow.

ABSTRACT: Important processes in nature and technology involve the adhesive capture of flowing particles or cells on the walls of a conduit. This paper introduces engineered spherical microparticles whose capture rates are limited by their near surface motions in flow. Specifically, these microparticles are sparsely functionalized with nanoscopic regions ("patches") of adhesive functionality, without which they would be nonadhesive. Not only is particle capture on the wall of a shear-chamber limited by surface chemistry as opposed to transport, but also the capture rates depend specifically on particle rotations that result from the vorticity of the shear flow field. These particle rotations continually expose new particle surface to the opposing chamber wall, sampling the particle surface for an ad

SUBMITTER: Shave MK 

PROVIDER: S-EPMC6171355 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature