The impact of culture conditions on growth and metabolomic profiles of freshwater cyanobacteria.

ABSTRACT: Cultured cyanobacteria produce secondary metabolites with a wide range of biological activities and are an important source of natural products. In the context of secondary metabolite discovery, microbial culture conditions are expected to support optimum growth, induce maximum chemical diversity, and be suitable for the majority of cyanobacterial strains. We investigated the effect of nitrate and phosphate on biomass production and metabolomic profiles of three filamentous freshwater cyanobacterial strains: cf. Oscillatoria sp. UIC 10045, Scytonema sp. UIC 10036, and Nostoc sp. UIC 10110. A standardized inoculation procedure allowed for the assessment of cell mass production. Dried cyanobacterial cell mass was extracted and analyzed by liquid chromatography coupled wi

SUBMITTER: Crnkovic CM 

PROVIDER: S-EPMC6171529 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature