Assessment of inner and outer retinal layer metrics on the Cirrus HD-OCT Platform in normal eyes.

ABSTRACT:

Purpose

Ellipsoid zone (EZ) and outer retinal integrity are strongly linked to visual prognosis, but quantitative normative data is lacking. This study evaluates the EZ, outer retina, and inner retina in eyes without macular disease across a wide age spectrum.

Methods

An IRB-approved study was performed for eyes without macular pathology undergoing Spectral Domain Optical Coherence Tomography (SD-OCT) scans on the Cirrus HD-OCT system (Carl Zeiss Meditec, Oberkochen, Germany). Scans were analyzed using a previously described automated EZ mapping tool with line-by-line manual verification. Segmentation included internal limiting membrane (ILM), outer nuclear layer/Henle fiber layer complex (ONL/HFL), EZ, and the retinal pigment epithelium (RPE). The output included metrics fo

SUBMITTER: Arepalli S 

PROVIDER: S-EPMC6171834 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature