Asmic: An Exceptional Building Block for Isocyanide Alkylations.

ABSTRACT: Asmic addresses the long-standing challenge of alkylating isocyanides, providing access to isocyanides with diverse substitution patterns. The o-anisylsulfanyl group serves a critical dual role by facilitating deprotonation-alkylation and providing a latent nucleophilic site through an unusual arylsulfanyl-lithium exchange.

SUBMITTER: Alwedi E 

PROVIDER: S-EPMC6172042 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature