Prognostic influence of 3-dimensional tumor volume on breast cancer compared to conventional 1-dimensional tumor size.

ABSTRACT:

Purpose

The prognostic influence of 3-dimensional tumor volume (Tv) on breast cancer compared to conventional 1-dimensional tumor size (T) was investigated.

Methods

Analysis was performed on a cohort of 8,996 primary breast cancer patients who were initially diagnosed with TNM stage I-III. Tumor size was defined as the maximum tumor dimension, and Tv was calculated by the equation of (4π × r1 × r2 × r3)/3; r1, r2, and r3 were defined as half of the largest, intermediate, and shortest dimension of the tumor, respectively. Tv was classified into Tv1, Tv2, and Tv3 according to the cut off values of 2.056 cm³ and 20.733 cm³.

Results

The survival curves according to both the T and Tv categories were clearly differentiated (all P < 0.001), as were thos

SUBMITTER: Hwang KT 

PROVIDER: S-EPMC6172357 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature