Abnormal Oculomotor Functions in Amyotrophic Lateral Sclerosis.

ABSTRACT:

Background and purpose

Although traditionally regarded as spared, a range of oculomotor dysfunction has been recognized in amyotrophic lateral sclerosis (ALS) patients. ALS is nowadays considered as a neurodegenerative disorder of a third compartment comprising widespread areas of extra-motor brain including cerebellum. Our objective was to perform an observational study to examine for ocular motor dysfunction in patients with ALS and for any differences between bulbar-onset and spinal-onset patients.

Methods

Thirty two ALS patients (bulbar onset: 10, spinal onset: 22) underwent the standardized systemic evaluations using video-oculography.

Results

Oculomotor dysfunctions such as square wave jerks, saccadic dysmetria, abnormal cogwheeling smooth pursuits and head shak

SUBMITTER: Kang BH 

PROVIDER: S-EPMC6172508 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature