Multimodal Assessment of Neural Substrates in Computerized Cognitive Training: A Preliminary Study.

ABSTRACT:

Background and purpose

Several studies have validated the clinical efficacy of computerized cognitive training applications. However, few studies have investigated the neural substrates of these training applications using simultaneous multimodal neuroimaging modalities. We aimed to determine the effectiveness of computerized cognitive training and corresponding neural substrates through a multimodal approach.

Methods

Ten patients with mild cognitive impairment (MCI), six patients with subjective memory impairment (SMI), and 10 normal controls received custom-developed computerized cognitive training in the memory clinic of a university hospital. All of the participants completed 24 sessions of computerized cognitive training, each lasting 40 minutes and performed twice week

SUBMITTER: Na HR 

PROVIDER: S-EPMC6172514 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature