Bacteriophages Synergize with the Gut Microbial Community To Combat Salmonella.

ABSTRACT: Salmonella infection is one of the main causes of food-borne diarrheal diseases worldwide. Although most Salmonella infections can be cleared without treatment, some cause serious illnesses that require antibiotic treatment. In view of the growing emergence of antibiotic-resistant Salmonella strains, novel treatments are increasingly required. Furthermore, there is a striking paucity of data on how a balanced human gut microbiota responds to Salmonella infection. This study aimed to evaluate whether a balanced gut microbiota protects against Salmonella growth and to compare two antimicrobial approaches for managing Salmonella infection: bacteriophage (phage) treatment and antibiotic treatment. Anaerobically cultivated human intestinal microflora (A

SUBMITTER: Hu YOO 

PROVIDER: S-EPMC6172775 | biostudies-literature | 2018 Sep-Oct

REPOSITORIES: biostudies-literature