Ontology highlight
ABSTRACT:
SUBMITTER: Shin SH
PROVIDER: S-EPMC6173745 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Nature communications 20181005 1
Despite many efforts to develop hormone therapy and chemotherapy, no effective strategy to suppress prostate cancer metastasis has been established because the metastasis is not well understood. We here investigate a role of CBP/p300-interacting transactivator with E/D-rich carboxy-terminal domain-2 (CITED2) in prostate cancer metastasis. CITED2 is highly expressed in metastatic prostate cancer, and its expression is correlated with poor survival. The CITED2 gene is highly activated by ETS-relat ...[more]