Pelvic radiotherapy for cervical cancer affects importantly the reproducibility of cytological alterations evaluation.

ABSTRACT:

Background

to evaluate the intraobserver and interobserver reproducibility of cervical cytopathology according to previous knowledge of whether patients received radiotherapy (RT) treatment or not.

Methods

The study analyzed a sample of 95 cervix cytological slides; 24 with cytological abnormalities (CA) and presence of RT; 21 without CA and presence of RT; 25 without CA and without previous RT; 25 with CA and without previous RT. Two cytopathology (CP) evaluations of the slides were carried out. For the first CP re-evaluation, the cytotechnologist was blinded for the information of previous RT. For the second CP re-evaluation, the cytotechnologist was informed about previous RT. The results were analyzed through inter and intraobserver agreement using the unweighted and wei

SUBMITTER: Lucena FA 

PROVIDER: S-EPMC6173841 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature