Salivary cortisol in post-traumatic stress disorder: a systematic review and meta-analysis.

ABSTRACT:

Background

Studies investigating salivary cortisol level as susceptibility marker for post-traumatic stress disorder (PTSD) produced inconsistent results. The aim of this study was to compare salivary cortisol concentration levels in PTSD patients with those in controls by synthesizing published data.

Methods

We did a systematic review, meta-analysis and meta-regression of studies comparing concentrations of salivary cortisol between patients with PTSD and controls. The electronic databases of PubMed, Embase, Web of Science and Psyc-ARTICLES were searched for relevant articles. A random-effects model with restricted maximum-likelihood estimator is used to synthesize the effect size (assessed by standardized mean difference).

Results

A total of 784 articles were identi

SUBMITTER: Pan X 

PROVIDER: S-EPMC6173866 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature