Reconstruction of avian ancestral karyotypes reveals differences in the evolutionary history of macro- and microchromosomes.

ABSTRACT:

Background

Reconstruction of ancestral karyotypes is critical for our understanding of genome evolution, allowing for the identification of the gross changes that shaped extant genomes. The identification of such changes and their time of occurrence can shed light on the biology of each species, clade and their evolutionary history. However, this is impeded by both the fragmented nature of the majority of genome assemblies and the limitations of the available software to work with them. These limitations are particularly apparent in birds, with only 10 chromosome-level assemblies reported thus far. Algorithmic approaches applied to fragmented genome assemblies can nonetheless help define patterns of chromosomal change in defined taxonomic groups.

Results

Here, we make use of

SUBMITTER: Damas J 

PROVIDER: S-EPMC6173868 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature