Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes.

ABSTRACT:

Background

It has been suggested that the acidity of the diet may be related to increased risk of type 2 diabetes. To investigate this hypothesis, we tested if the acidity of the diet, measured as the Potential Renal Acid Load (PRAL) score, was associated with incident diabetes and diabetes-related intermediary traits.

Methods

A total of 54,651 individuals from the Danish Diet, Cancer and Health (DCH) cohort were included in the prospective cox regression analyses of incident diabetes over a 15 years follow-up period. Moreover, 5724 Danish individuals with baseline data from the Inter99 cohort were included in the cross sectional, multivariate and logistic regression analyses of measures of insulin sensitivity, insulin release and glucose tolerance status derived from an ora

SUBMITTER: Gæde J 

PROVIDER: S-EPMC6173920 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature