Bone Marrow Aspiration Does Not Induce a Measurable Pain Response Compared to Sham Procedure.

ABSTRACT: Bone marrow is commonly collected from horses for regenerative medicine applications. Little information is available regarding pain experienced by the horse during bone marrow aspiration. The objective of this study was to characterize horse reaction and pain response during bone marrow aspiration (BMA) compared to a sham (SHAM) procedure. We hypothesized there would be significantly greater horse reaction or pain response measured by salivary cortisol, heart rate variability, and depth and duration of sedation between BMA and SHAM. Twelve university owned horses underwent a BMA and sham procedure, 4 weeks apart in a randomized cross-over design, while sedated with 0.4 mg/kg xylazine hydrochloride. As measures of sedation depth, head height was recorded and sedation level was scored at sp

SUBMITTER: Rowland AL 

PROVIDER: S-EPMC6174850 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature