Risk factors for development and progression of diabetic retinopathy in Dutch patients with type 1 diabetes mellitus.

ABSTRACT:

Purpose

To investigate risk factors for the development and progression of diabetic retinopathy (DR) and long-term visual outcomes in Dutch patients with type 1 diabetes mellitus (T1DM).

Methods

Cumulative incidences were calculated for DR, vision-threatening DR (VTDR), defined as (pre)proliferative DR and diabetic macular oedema, and best-corrected visual acuity (BCVA) <0.5 and <0.3 at the most recent eye examination. The following factors were assessed: duration of diabetes, age of onset of T1DM, gender, mean HbA1c, HbA1c variability (defined as coefficient of variation of five separate HbA1c measurements), mean arterial blood pressure, body mass index, albuminuria and lipid profile. We used multivariable Cox regression models to identify factors associated with DR develop

SUBMITTER: Schreur V 

PROVIDER: S-EPMC6174939 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature