The genetic architecture of genome-wide recombination rate variation in allopolyploid wheat revealed by nested association mapping.

ABSTRACT: Recombination affects the fate of alleles in populations by imposing constraints on the reshuffling of genetic information. Understanding the genetic basis of these constraints is critical for manipulating the recombination process to improve the resolution of genetic mapping, and reducing the negative effects of linkage drag and deleterious genetic load in breeding. Using sequence-based genotyping of a wheat nested association mapping (NAM) population of 2,100 recombinant inbred lines created by crossing 29 diverse lines, we mapped QTL affecting the distribution and frequency of 102 000 crossovers (CO). Genome-wide recombination rate variation was mostly defined by rare alleles with small effects together explaining up to 48.6% of variation. Most QTL were additive and showed predominantly

SUBMITTER: Jordan KW 

PROVIDER: S-EPMC6174997 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature