Gradient nonlinearity effects on upper cervical spinal cord area measurement from 3D T₁ -weighted brain MRI acquisitions.

ABSTRACT:

Purpose

To explore (i) the variability of upper cervical cord area (UCCA) measurements from volumetric brain 3D T₁ -weighted scans related to gradient nonlinearity (GNL) and subject positioning; (ii) the effect of vendor-implemented GNL corrections; and (iii) easily applicable methods that can be used to retrospectively correct data.

Methods

A multiple sclerosis patient was scanned at seven sites using 3T MRI scanners with the same 3D T₁ -weighted protocol without GNL-distortion correction. Two healthy subjects and a phantom were additionally scanned at a single site with varying table positions. The 2D and 3D vendor-implemented GNL-correction algorithms and retrospective methods based on (i) phantom data fit, (ii) normalization with C2 vertebral body d

SUBMITTER: Papinutto N 

PROVIDER: S-EPMC6175276 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature