Longitudinal structural brain development and externalizing behavior in adolescence.

ABSTRACT:

Background

Cross-sectional studies report relations between externalizing behavior and structural abnormalities in cortical thickness of prefrontal regions and volume reductions in subcortical regions. To understand how these associations emerge and develop, longitudinal designs are pivotal.

Method

In the current longitudinal study, a community sample of children, adolescents and young adults (N = 271) underwent magnetic resonance imaging (MRI) in three biennial waves (680 scans). At each wave, aspects of externalizing behavior were assessed with parent-reported aggression and rule-breaking scores (Child Behavior Checklist), and self-reported aggression scores (Buss-Perry Aggression Questionnaire). Regions of interest (ROIs) were selected based on prior research: dorsolatera

SUBMITTER: Bos MGN 

PROVIDER: S-EPMC6175471 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature