Cortical morphology, epileptiform discharges, and neuropsychological performance in BECTS.

ABSTRACT:

Objectives

The aim of this study was to understand the relationship between cortical morphology, centrotemporal spike (CTS), and neuropsychological functioning in children with BECTS compared to their typically developing peers.

Materials and methods

To examine whole-brain differences in cortical thickness between groups, a general linear model approach was applied to T1-weighted structural magnetic resonance imaging (MRI) in children with BECTS and typically developing children. Further region-of-interest (ROI) analyses were performed to examine the effects of frequency and lateralization of CTS. In addition, the relationship between Processing Speed Index (PSI) and cortical thickness was investigated.

Results

Twenty-three patients with BECTS and thirty-two controls

SUBMITTER: Fujiwara H 

PROVIDER: S-EPMC6175642 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature