A high circulating FGF21 level as a prognostic marker in patients with acute myocardial infarction.

ABSTRACT:

Objective

The purpose of this study was to examine the level of serum FGF21 in acute myocardial infarction (AMI) and to explore the association between serum FGF21 and major adverse cardiovascular events in AMI patients.

Methods

A total of 238 Chinese patients were recruited for this study between January 2016 and June 2016, including 183 AMI patients and 55 patients without AMI were enrolled in this study. The level of serum FGF21 was measured by ELISA. Patients were followed-up after admission using a standardized protocol that included Outpatient follow-up and telephone contacts to record the Major Adverse Cardiovascular Events (MACEs). Finally, 165 patients were enrolled and followed up during the period of 24 months.

Results

Circulating FGF21 level was elevated i

SUBMITTER: Chen H 

PROVIDER: S-EPMC6176227 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature