Hippocampal CA1 gamma power predicts the precision of spatial memory judgments.

ABSTRACT: The hippocampus plays a critical role in spatial memory. However, the exact neural mechanisms underlying high-fidelity spatial memory representations are unknown. We report findings from presurgical epilepsy patients with bilateral hippocampal depth electrodes performing an object-location memory task that provided a broad range of spatial memory precision. During encoding, patients were shown a series of objects along the circumference of an invisible circle. At test, the same objects were shown at the top of the circle (0°), and patients used a dial to move the object to its location shown during encoding. Angular error between the correct location and the indicated location was recorded as a continuous measure of performance. By registering pre- and postimplantation MRI scans, we were a

SUBMITTER: Stevenson RF 

PROVIDER: S-EPMC6176623 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature