An Open-Label Study of Sufentanil Sublingual Tablet 30 Mcg in Patients with Postoperative Pain.

ABSTRACT:

Objective

To evaluate sufentanil sublingual tablet 30 mcg (SST 30 mcg) for postoperative pain in an older patient population with comorbidities.

Design

Multicenter, open-label, single-arm study.

Setting

Nine hospitals across the United States.

Subjects

Adults aged ≥40 years who had undergone a surgical procedure.

Methods

Patients with a postoperative pain intensity score ≥4 on an 11-point numeric rating scale (NRS) were allowed to enter the study and receive SST 30 mcg as requested for pain (minimum 60-minute redosing interval) over the 12-hour study period. Efficacy was assessed by patient reports of pain intensity on the NRS and a five-point pain relief scale. Safety was monitored throughout the study; plasma sufentanil concentrations were also measure

SUBMITTER: Hutchins JL 

PROVIDER: S-EPMC6176750 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature