Reversal of pulmonary arterial hypertension in POEMS syndrome with thalidomide: a case report.

ABSTRACT:

Introduction

Pulmonary arterial hypertension (PAH) is a progressive and life-threatening disease characterized by the remodelling of distal pulmonary arteries in the absence of other cardiopulmonary disease, usually leading to right ventricular failure. Given the current European Society of Cardiology and the European Respiratory Society guidelines for the diagnosis and treatment of pulmonary hypertension (PH), most of the patients with severe PAH usually require to have a lifelong combination therapy that includes prostacyclin, phosphodiesterase-5 inhibitor, and endothelin receptor antagonist. However, the reversibility of PAH has been reported through the treatment of the underlying diseases or comorbidities.

Case presentation

We present a case of a 45-year-old woman with

SUBMITTER: Tanaka TD 

PROVIDER: S-EPMC6177100 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature