Carious status and supragingival plaque microbiota in hemodialysis patients.

ABSTRACT:

Objective

The aim of this study was to evaluate the carious status and the microbial profiles of supragingival plaque in patients with chronic kidney disease undergoing hemodialysis.

Methods

This study included 30 patients with chronic kidney disease undergoing hemodialysis as well as 30 control subjects. Dental examination was performed and the decayed-missing-filled-teeth was recorded. Supragingival plaque was taken and analyzed using 16S rRNA gene amplicon by Illumina MiSeq sequencing to detect microbial composition and community diversity and structure.

Results

The level of decayed-missing-filled-teeth was higher in the hemodialysis group than that in the control group. Microbial analysis showed a decrease in α diversity and a increase in relative abundance and pr

SUBMITTER: Yue Q 

PROVIDER: S-EPMC6177147 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature