Effect of sensor location on continuous intraperitoneal glucose sensing in an animal model.

ABSTRACT:

Background

In diabetes research, the development of the artificial pancreas has been a major topic since continuous glucose monitoring became available in the early 2000's. A prerequisite for an artificial pancreas is fast and reliable glucose sensing. However, subcutaneous continuous glucose monitoring carries the disadvantage of slow dynamics. As an alternative, we explored continuous glucose sensing in the peritoneal space, and investigated potential spatial differences in glucose dynamics within the peritoneal cavity. As a secondary outcome, we compared the glucose dynamics in the peritoneal space to the subcutaneous tissue.

Material and methods

Eight-hour experiments were conducted on 12 anesthetised non-diabetic pigs. Four commercially available amperometric glucose se

SUBMITTER: Am MK 

PROVIDER: S-EPMC6177183 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature