Identification of mycolic acid forms using surface-enhanced Raman scattering as a fast detection method for tuberculosis.

ABSTRACT:

Background

Tuberculosis (TB) is the ninth leading cause of death worldwide and the leading cause from a single infectious agent, based on the WHO Global Tuberculosis Report in 2017. TB causes massive health care burdens in many parts of the world, specifically in the resource constrained developing world. Most deaths from TB could be prevented with cost effective early diagnosis and appropriate treatment.

Purpose

Conventional TB detection methods are either too slow as it takes a few weeks for diagnosis or they lack the specificity and accuracy. Thus the objective of this study was to develop a fast and efficient detection for TB using surface enhanced Raman scattering (SERS) technique.

Methods

SERS spectra for different forms of mycolic acids (MAs) that are both synt

SUBMITTER: Perumal J 

PROVIDER: S-EPMC6177374 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature