Circadian rhythms and psychiatric profiles in young adults with unipolar depressive disorders.

ABSTRACT: Abnormalities in circadian rhythms have been reported in people with mood disorders, but these abnormalities are marked by considerable inter-individual variability. This study aimed to identify pathophysiological subgroups on the basis of circadian markers and evaluate how these subgroups relate to psychiatric profiles. Thirty-five young adults (18-31 years old) receiving clinical care for unipolar depressive disorders and 15 healthy controls took part to this study. The Hamilton Rating Scale for Depression and the Young Mania rating scale were used to evaluate the severity of mood symptoms in participants with depressive disorders. All participant underwent ambulatory sleep monitoring with actigraphy for about 12 days before attending a laboratory-based chronobiological assessment which

SUBMITTER: Robillard R 

PROVIDER: S-EPMC6177460 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature