The copper-deprivation stimulon of Corynebacterium glutamicum comprises proteins for biogenesis of the actinobacterial cytochrome bc₁-aa₃ supercomplex.

ABSTRACT: Aerobic respiration in Corynebacterium glutamicum involves a cytochrome bc₁-aa₃ supercomplex with a diheme cytochrome c₁, which is the only c-type cytochrome in this species. This organization is considered as typical for aerobic Actinobacteria. Whereas the biogenesis of heme-copper type oxidases like cytochrome aa₃ has been studied extensively in α-proteobacteria, yeast, and mammals, nothing is known about this process in Actinobacteria. Here, we searched for assembly proteins of the supercomplex by identifying the copper-deprivation stimulon, which might include proteins that insert copper into cytochrome aa₃ Using gene expression profiling, we found two copper starvation-induced prote

SUBMITTER: Morosov X 

PROVIDER: S-EPMC6177595 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature