A mathematical model for predicting the adult height of girls with idiopathic central precocious puberty: A European validation.

ABSTRACT:

Background

A previous single-center study established a mathematical model for predicting the adult height (AH) in girls with idiopathic central precocious puberty (CPP).

Objective

To perform internal and external validations by comparing the actual AH to the calculated AH established by this model and to update it.

Methods

The original formula, calculated AH (cm) = 2.21 (height at initial evaluation, SD) + 2.32 (target height, SD) - 1.83 (luteinizing hormone/follicle-stimulating hormone peaks ratio) + 159.68, was established in a sample of 134 girls (group 4) and was applied to additional girls with CPP seen in the same center (group 1, n = 35), in Germany (group 2, n = 43) and in the Netherlands (group 3, n = 72). This formula has been updated based on these extende

SUBMITTER: Lemaire P 

PROVIDER: S-EPMC6178384 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature