Elastic Abdominal Binders Attenuate Orthostatic Hypotension in Parkinson's Disease.

ABSTRACT:

Background and methods

To investigate the possible efficacy of an elastic abdominal binder to control orthostatic hypotension (OH) associated with Parkinson's disease (PD), 15 patients with PD and OH were enrolled in a single-blind crossover study with elastic abdominal versus placebo binder on two different days, separated by a 1-day interval, followed by a 4-week open-label follow-up.

Results

Intervention significantly reduced blood pressure fall upon tilting. The mean difference (standard deviation; 95% confidence intervals) between abdominal binder versus placebo was +10 mm Hg (10.2; +3.5, +16.5; P = 0.006). No significant effect on supine mean blood pressure values was observed compared to placebo (P = 0.3). Symptoms of OH decreased significantly during fo

SUBMITTER: Fanciulli A 

PROVIDER: S-EPMC6178725 | biostudies-literature | 2016 Mar-Apr

REPOSITORIES: biostudies-literature