Base-Directed Formation of Fluorescent Silver Clusters.

ABSTRACT: Small silver clusters that form with short oligonucleotides are distinguished by their strong fluorescence. Previous work showed that red and blue/green emitting species form with the cytosine oligonucleotide dC₁₂. To understand how the bases and base sequence influence cluster formation, the blue/green emitting clusters that form with the thymine-containing oligonucleotides dT12, dT₄C₄T₄, and dC₄T₄C₄ are discussed. With dT₁₂ and dT₄C₄T₄, variations in the solution pH establish that the clusters associate with the N3 of thymine. The small clusters are bound to the larger DNA template, as demonstrated by fluorescence anisotropy, circular dichroism, and fluorescence correl

SUBMITTER: Sengupta B 

PROVIDER: S-EPMC6178949 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature